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HomeInvestmentValneva studies additional heterologous booster knowledge from research of COVID-19 vaccine

Valneva studies additional heterologous booster knowledge from research of COVID-19 vaccine


Valneva reported additional heterologous booster knowledge from an exploratory, small medical research for its inactivated COVID-19 vaccine, VLA2001. In research VLA2001-3071, a subset of individuals, or three out of 9 teams, obtained VLA2001 following two or three doses of mRNA COVID-19 vaccine, with or with out break-through an infection, together with 25-50 individuals per group. The info present {that a} booster dose of VLA2001 was effectively tolerated in beforehand BNT162b2 – Pfizer/BioNTech – or mRNA 1273 – Moderna – vaccinated individuals, “confirming the favorable security profile of VLA2001 seen throughout all research – together with in homologous or heterologous booster settings,” the corporate mentioned. “Nevertheless, on this research, a further booster dose of VLA2001 elicited solely a touch elevated neutralizing antibody response,” Valneva added. The corporate beforehand reported optimistic heterologous booster outcomes following major vaccination with ChAdOx1-S – AstraZeneca – in August 20223 and optimistic homologous booster outcomes on the finish of December 20214. Valneva is at present searching for regulatory approval for VLA2001 as a homologous booster in addition to heterologous booster in ChAdOx1-S – AstraZeneca – primed people which can help the corporate in deploying its stock in worldwide markets. Juan Carlos Jaramillo, M.D., Valneva’s Chief Medical Officer, commented, “Whereas these newest booster outcomes aren’t aligned with the encouraging homologous and heterologous booster outcomes seen beforehand, we’re happy to as soon as once more affirm the favorable security and tolerability profile of VLA2001, which was necessary for EMA and MHRA approval.”

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